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The Food and Drug Administration, FDA, has approved the drug Vivitrol for your treatment of opioid dependence based on a news release by them on 10-12-2010.

Using two separate drugs to lose weight can be very effective there are combinations in front of the FDA now awaiting approval. When dealing with weight-loss and the people who go through it one should err assisting caution and let the FDA do its job and demand some study be done so your public recognizes the side effects and dangers of the medications before we bring them. Keep in mind that drug companies come in business to make money and that they would say almost anything to keep people on his or her medications.

Researchers found out that participants taking this drug for any year, lost excess weight within a month and have kept the extra weight off through the 56 weeks of the study. Contrave is really a combination in the drugs naltrexone and bupropion, which generally seems to reflect a new trend of weight-loss drugs that are made up of multiple active ingredient, which may make them more efficient and safer.

Combo-pilling is the newest fad or in addition to this the newest ahead under scrutiny and therefore it is just more publicly known recently, comb-pilling to lose weight has been around since the eighties. The biggest reason that utilizing a combination of pills is starting to become popular will be the fact that as of right now there are no long term prescription diet pills that have been authorized by the FDA aside from orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications even though some of the combinations are already rejected or have yet to be approved by the FDA.

Seizures are a side effect with Contrave and mustn't be taken in individuals with seizure disorders. The drug could also raise blood pressure levels and heartrate, and really should not be used in individuals with a history of cardiac arrest or stroke in the last six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy with the drug.

The FDA also warned that Contrave can raise blood pressure and heartbeat and must not used in patients with uncontrolled high hypertension, as well as by you are not heart-related and cerebrovascular (circulation dysfunction impacting mental performance) disease. Patients using a history of cardiac arrest or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes using a boxed warning to alert health care professionals and patients towards the increased likelihood of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for smoking cessation.


From a psychiatric viewpoint, evidence shows that the ordinary neural mechanism for goal-directed behavior has been hijacked with the addiction, and malfunctions so that its ordinary functions are exaggerated and fixated on its object. An object creates a stimulus and the person engages in a "goal-directed behavioral response" that creates a "natural high"(Bostwick & Bucci, 2008).